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Antimicrobial Agents and Chemotherapy, March 2002, p. 884-886, Vol. 46, No. 3
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.3.884-886.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma

Rob E. Aarnoutse,1* Corrien P. W. G. M. Verweij-van Wissen,1 Eleonora W. J. van Ewijk-Beneken Kolmer,1 Eveline W. Wuis,1 Peter P. Koopmans,2 Yechiel A. Hekster,1 and David M. Burger1

Department of Clinical Pharmacy,1 Department of General Internal Medicine, University Medical Centre Nijmegen, Nijmegen, The Netherlands2

Received 7 June 2001/ Returned for modification 3 October 2001/ Accepted 3 December 2001

An international interlaboratory quality control program for measurement of antiretroviral drugs was initiated. The first round was confined to protease inhibitors and showed large variability in the performance of participating laboratories. The results demonstrate the need for and utility of an ongoing quality control program in this area of bioanalysis.

* Corresponding author. Mailing address: Department of Clinical Pharmacy, University Medical Centre Nijmegen, P. O. Box 9101, 533 KF, 6500 HB, Nijmegen, The Netherlands. Phone: 31-24-3616405. Fax: 31-24-3540331. E-mail: R.Aarnoutse{at}klinfarm.azn.nl.

Antimicrobial Agents and Chemotherapy, March 2002, p. 884-886, Vol. 46, No. 3
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.3.884-886.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Copyright © 2002 by the American Society for Microbiology. All rights reserved.