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Antimicrobial Agents and Chemotherapy, May 2003, p. 1749-1751, Vol. 47, No. 5
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.5.1749-1751.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

High Prevalence of PER-1 Extended-Spectrum ß-Lactamase-Producing Acinetobacter spp. in Korea

Dongeun Yong,1,2 Jong Hee Shin,3 Sinyoung Kim,1,2 Youngsik Lim,4 Jong Hwa Yum,2,4 Kyungwon Lee,1,2,4* Yunsop Chong,1,2 and Adolf Bauernfeind5

Department of Laboratory Medicine,1 Research Institute of Bacterial Resistance,2 BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul,4 Department of Laboratory Medicine, Chonnam University Medical School, Kwangju, Korea,3 MICOER Institute, Munich, Germany5

Received 28 October 2002/ Returned for modification 10 December 2002/ Accepted 18 February 2003

PER-1, an extended-spectrum ß-lactamase, has been reported only in Europe. We detected PER-1 in 53 of 97 acinetobacters in Korea, mainly in the sputum of intensive care unit patients. Pulsed-field gel electrophoresis analysis suggested that clonal spread had occurred. Only PCR reliably detected PER-1 producers. PER-1 producers may also exist in other Asian countries.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Yonsei University College of Medicine, 134 Shinchondong, Seodaemunku, Seoul, 120-752, Korea. Phone: 82-2-361-5866. Fax: 82-2-313-0908. E-mail: leekcp{at}yumc.yonsei.ac.kr.

Antimicrobial Agents and Chemotherapy, May 2003, p. 1749-1751, Vol. 47, No. 5
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.5.1749-1751.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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