This Article Full Text Full Text (PDF) Supplemental material Other Versions of this Article: AAC.00036-08v1 52/8/2937    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Google Scholar Articles by Mokrousov, I. Articles by Rastogi, N. PubMed PubMed Citation Articles by Mokrousov, I. Articles by Rastogi, N.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, August 2008, p. 2937-2939, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.00036-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Molecular Characterization of Ofloxacin-Resistant Mycobacterium tuberculosis Strains from Russia ^,

Laboratory of Molecular Microbiology, St. Petersburg Pasteur Institute, 197101 St. Petersburg, Russia,¹ Unité de la Tuberculose et des Mycobactéries, Institut Pasteur de Guadeloupe, Abymes 97183, Guadeloupe, France,² Laboratory of Microbiology of Tuberculosis, The Research Institute of Phthisiopulmonology, 193036 St. Petersburg, Russia³

Received 9 January 2008/ Returned for modification 27 February 2008/ Accepted 5 June 2008

In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis.

Published ahead of print on 16 June 2008.

Supplemental material for this article may be found at http://aac.asm.org/.