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Research Article:

L L Silver and K A Bostian

Discovery and development of new antibiotics: the problem of antibiotic resistance.
Antimicrob. Agents Chemother. 1993 37: 377-383. [PDF] [Reprints and Permissions]  

Y Fukuoka, Y Ikeda, Y Yamashiro, M Takahata, Y Todo, and H Narita

In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
Antimicrob. Agents Chemother. 1993 37: 384-392. [Abstract] [PDF] [Reprints and Permissions]  

G Matera, J A Cook, J Geisel, S H Ashton, W C Wise, A Focá, B A Berkowitz, and P V Halushka

Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages.
Antimicrob. Agents Chemother. 1993 37: 393-397. [Abstract] [PDF] [Reprints and Permissions]  

S T Brown, F F Edwards, E M Bernard, W Tong, and D Armstrong

Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine.
Antimicrob. Agents Chemother. 1993 37: 398-402. [Abstract] [PDF] [Reprints and Permissions]  

P Chavalitshewinkoon, P Wilairat, S Gamage, W Denny, D Figgitt, and R Ralph

Structure-activity relationships and modes of action of 9-anilinoacridines against chloroquine-resistant Plasmodium falciparum in vitro.
Antimicrob. Agents Chemother. 1993 37: 403-406. [Abstract] [PDF] [Reprints and Permissions]  

V Lalande, C Truffot-Pernot, A Paccaly-Moulin, J Grosset, and B Ji

Powerful bactericidal activity of sparfloxacin (AT-4140) against Mycobacterium tuberculosis in mice.
Antimicrob. Agents Chemother. 1993 37: 407-413. [Abstract] [PDF] [Reprints and Permissions]  

N Honore and S T Cole

Molecular basis of rifampin resistance in Mycobacterium leprae.
Antimicrob. Agents Chemother. 1993 37: 414-418. [Abstract] [PDF] [Reprints and Permissions]  

K R Reuhl, M Vapiwala, M T Ryzlak, and C P Schaffner

Comparative neurotoxicities of amphotericin B and its mono-methyl ester derivative in rats.
Antimicrob. Agents Chemother. 1993 37: 419-428. [Abstract] [PDF] [Reprints and Permissions]  

C W Hendrix, J B Margolick, B G Petty, R B Markham, L Nerhood, H Farzadegan, P O Ts'o, and P S Lietman

Biologic effects after a single dose of poly(I):poly(C12U) in healthy volunteers.
Antimicrob. Agents Chemother. 1993 37: 429-435. [Abstract] [PDF] [Reprints and Permissions]  

K Vance-Bryan, D R Guay, S S Gilliland, K A Rodvold, and J C Rotschafer

Effect of obesity on vancomycin pharmacokinetic parameters as determined by using a Bayesian forecasting technique.
Antimicrob. Agents Chemother. 1993 37: 436-440. [Abstract] [PDF] [Reprints and Permissions]  

R W Jansen, L C Johnson, and D R Averett

High-capacity in vitro assessment of anti-hepatitis B virus compound selectivity by a virion-specific polymerase chain reaction assay.
Antimicrob. Agents Chemother. 1993 37: 441-447. [Abstract] [PDF] [Reprints and Permissions]  

R C Stevens, S C Laizure, P L Sanders, and D S Stein

Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers.
Antimicrob. Agents Chemother. 1993 37: 448-452. [Abstract] [PDF] [Reprints and Permissions]  

R E Hancock and S W Farmer

Mechanism of uptake of deglucoteicoplanin amide derivatives across outer membranes of Escherichia coli and Pseudomonas aeruginosa.
Antimicrob. Agents Chemother. 1993 37: 453-456. [Abstract] [PDF] [Reprints and Permissions]  

Y Wang, W M Huang, and D E Taylor

Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.
Antimicrob. Agents Chemother. 1993 37: 457-463. [Abstract] [PDF] [Reprints and Permissions]  

J M Kinowski, J E de la Coussaye, F Bressolle, D Fabre, G Saissi, O Bouvet, M Galtier, and J J Eledjam

Multiple-dose pharmacokinetics of amikacin and ceftazidime in critically ill patients with septic multiple-organ failure during intermittent hemofiltration.
Antimicrob. Agents Chemother. 1993 37: 464-473. [Abstract] [PDF] [Reprints and Permissions]  

G H Talbot, P A Cassileth, L Paradiso, R Correa-Coronas, and L Bond

Oral enoxacin for infection prevention in adults with acute nonlymphocytic leukemia. The Enoxacin Prophylaxis Study Group.
Antimicrob. Agents Chemother. 1993 37: 474-482. [Abstract] [PDF] [Reprints and Permissions]  

G L Drusano, D E Johnson, M Rosen, and H C Standiford

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis.
Antimicrob. Agents Chemother. 1993 37: 483-490. [Abstract] [PDF] [Reprints and Permissions]  

H Torres and D Raoult

In vitro activities of ceftriaxone and fusidic acid against 13 isolates of Coxiella burnetii, determined using the shell vial assay.
Antimicrob. Agents Chemother. 1993 37: 491-494. [Abstract] [PDF] [Reprints and Permissions]  

E Roilides, P Paschalides, A Freifeld, and P A Pizzo

Suppression of polymorphonuclear leukocyte bactericidal activity by suramin.
Antimicrob. Agents Chemother. 1993 37: 495-500. [Abstract] [PDF] [Reprints and Permissions]  

J D Peter, F Jehl, T Pottecher, J P Dupeyron, and H Monteil

Pharmacokinetics of intravenous fusidic acid in patients with cholestasis.
Antimicrob. Agents Chemother. 1993 37: 501-506. [Abstract] [PDF] [Reprints and Permissions]  

A Pefanis, C Thauvin-Eliopoulos, G M Eliopoulos, and R C Moellering, Jr

Activity of ampicillin-sulbactam and oxacillin in experimental endocarditis caused by beta-lactamase-hyperproducing Staphylococcus aureus.
Antimicrob. Agents Chemother. 1993 37: 507-511. [Abstract] [PDF] [Reprints and Permissions]  

R G Hewitt, G D Morse, W D Lawrence, M L Maliszewski, J Santora, L Bartos, E Bonnem, and B Poiesz

Pharmacokinetics and pharmacodynamics of granulocyte-macrophage colony-stimulating factor and zidovudine in patients with AIDS and severe AIDS-related complex.
Antimicrob. Agents Chemother. 1993 37: 512-522. [Abstract] [PDF] [Reprints and Permissions]  

R C Li, J J Schentag, and D E Nix

The fractional maximal effect method: a new way to characterize the effect of antibiotic combinations and other nonlinear pharmacodynamic interactions.
Antimicrob. Agents Chemother. 1993 37: 523-531. [Abstract] [PDF] [Reprints and Permissions]  

E Connor, S Morrison, J Lane, J Oleske, R L Sonke, and J Connor

Safety, tolerance, and pharmacokinetics of systemic ribavirin in children with human immunodeficiency virus infection.
Antimicrob. Agents Chemother. 1993 37: 532-539. [Abstract] [PDF] [Reprints and Permissions]  

M N Prichard, L E Prichard, and C Shipman, Jr

Strategic design and three-dimensional analysis of antiviral drug combinations.
Antimicrob. Agents Chemother. 1993 37: 540-545. [Abstract] [PDF] [Reprints and Permissions]  

M R Yeaman, A S Ibrahim, J E Edwards, Jr, A S Bayer, and M A Ghannoum

Thrombin-induced rabbit platelet microbicidal protein is fungicidal in vitro.
Antimicrob. Agents Chemother. 1993 37: 546-553. [Abstract] [PDF] [Reprints and Permissions]  

J M Steckelberg, M S Rouse, B M Tallan, D R Osmon, N K Henry, and W R Wilson

Relative efficacies of broad-spectrum cephalosporins for treatment of methicillin-susceptible Staphylococcus aureus experimental infective endocarditis.
Antimicrob. Agents Chemother. 1993 37: 554-558. [Abstract] [PDF] [Reprints and Permissions]  

N H Georgopapadakou and A Bertasso

Mechanisms of action of cephalosporin 3'-quinolone esters, carbamates, and tertiary amines in Escherichia coli.
Antimicrob. Agents Chemother. 1993 37: 559-565. [Abstract] [PDF] [Reprints and Permissions]  

H C Neu, N X Chin, and H B Huang

In vitro activity and beta-lactamase stability of FK-037, a parenteral cephalosporin.
Antimicrob. Agents Chemother. 1993 37: 566-573. [Abstract] [PDF] [Reprints and Permissions]  

L E Nicolle, J DuBois, A Y Martel, G K Harding, S D Shafran, and J M Conly

Treatment of acute uncomplicated urinary tract infections with 3 days of lomefloxacin compared with treatment with 3 days of norfloxacin.
Antimicrob. Agents Chemother. 1993 37: 574-579. [Abstract] [PDF] [Reprints and Permissions]  

J A Urbina, K Lazardi, E Marchan, G Visbal, T Aguirre, M M Piras, R Piras, R A Maldonado, G Payares, and W de Souza

Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.
Antimicrob. Agents Chemother. 1993 37: 580-591. [Abstract] [PDF] [Reprints and Permissions]  

T Sorsa, O Lindy, Y T Konttinen, K Suomalainen, T Ingman, H Saari, S Halinen, H M Lee, L M Golub, and J Hall

Doxycycline in the protection of serum alpha-1-antitrypsin from human neutrophil collagenase and gelatinase.
Antimicrob. Agents Chemother. 1993 37: 592-594. [Abstract] [PDF] [Reprints and Permissions]  

G E Kleter, J T Brouwer, R A Heijtink, S W Schalm, and W G Quint

Detection of hepatitis C virus RNA in patients with chronic hepatitis C virus infections during and after therapy with alpha interferon.
Antimicrob. Agents Chemother. 1993 37: 595-597. [Abstract] [PDF] [Reprints and Permissions]  

L A Collins, G J Malanoski, G M Eliopoulos, C B Wennersten, M J Ferraro, and R C Moellering, Jr

In vitro activity of RP59500, an injectable streptogramin antibiotic, against vancomycin-resistant gram-positive organisms.
Antimicrob. Agents Chemother. 1993 37: 598-601. [Abstract] [PDF] [Reprints and Permissions]  

F M Hamzeh, T Spector, and P S Lietman

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81) potently inhibits human cytomegalovirus replication and potentiates the antiviral effects of ganciclovir.
Antimicrob. Agents Chemother. 1993 37: 602-604. [Abstract] [PDF] [Reprints and Permissions]  

K C Lamp and M J Rybak

Teicoplanin and daptomycin bactericidal activities in the presence of albumin or serum under controlled conditions of pH and ionized calcium.
Antimicrob. Agents Chemother. 1993 37: 605-609. [Abstract] [PDF] [Reprints and Permissions]  

L B Rice, L L Carias, and D M Shlaes

Efficacy of ampicillin-sulbactam versus that of cefoxitin for treatment of Escherichia coli infections in a rat intra-abdominal abscess model.
Antimicrob. Agents Chemother. 1993 37: 610-612. [Abstract] [PDF] [Reprints and Permissions]  

K H Rand, H J Houck, P Brown, and D Bennett

Reproducibility of the microdilution checkerboard method for antibiotic synergy.
Antimicrob. Agents Chemother. 1993 37: 613-615. [Abstract] [PDF] [Reprints and Permissions]  

E Cantón

Cefotaxime breakpoint for Streptococcus pneumoniae.
Antimicrob. Agents Chemother. 1993 37: 616-617. [PDF] [Reprints and Permissions]  

Correction:

George S. Jaresko, Steven L. Barriere, and B. Lamar Johnson, JR.

Serum and Blister Fluid Pharmacokinetics and Bactericidal Activities of Ampicillin-Sulbactam, Cefotetan, Cefoxitin, Ceftizoxime, and Ticarcillin-Clavulanate
Antimicrob. Agents Chemother. 1993 37: 618. [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.