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Experimental Therapeutics:

John R. Graybill, Rosie Bocanegra, Laura K. Najvar, David Loebenberg, and Mike F. Luther

Granulocyte Colony-Stimulating Factor and Azole Antifungal Therapy in Murine Aspergillosis: Role of Immune Suppression
Antimicrob. Agents Chemother. 1998 42: 2467-2473. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naoki Nagahara, Yohko Akiyama, Masafumi Nakao, Mayumi Tada, Megumi Kitano, and Yasuyuki Ogawa

Mucoadhesive Microspheres Containing Amoxicillin for Clearance of Helicobacter pylori
Antimicrob. Agents Chemother. 1998 42: 2492-2494. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. K. Budhani and J. K. Struthers

Interaction of Streptococcus pneumoniae and Moraxella catarrhalis: Investigation of the Indirect Pathogenic Role of -Lactamase-Producing Moraxellae by Use of a Continuous-Culture Biofilm System
Antimicrob. Agents Chemother. 1998 42: 2521-2526. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yves Bergeron, Nathalie Ouellet, Anne-Marie Deslauriers, Marie Simard, Martin Olivier, and Michel G. Bergeron

Reduction by Cefodizime of the Pulmonary Inflammatory Response Induced by Heat-Killed Streptococcus pneumoniae in Mice
Antimicrob. Agents Chemother. 1998 42: 2527-2533. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hail M. Al-Abdely, John R. Graybill, Rosie Bocanegra, Laura Najvar, Eleanor Montalbo, Steven L. Regen, and Peter C. Melby

Efficacies of KY62 against Leishmania amazonensis and Leishmania donovani in Experimental Murine Cutaneous Leishmaniasis and Visceral Leishmaniasis
Antimicrob. Agents Chemother. 1998 42: 2542-2548. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vladimir Michailowsky, Silvane M. F. Murta, Leonardo Carvalho-Oliveira, Maria E. S. Pereira, Ludmila R. P. Ferreira, Zigman Brener, Alvaro J. Romanha, and Ricardo T. Gazzinelli

Interleukin-12 Enhances In Vivo Parasiticidal Effect of Benznidazole during Acute Experimental Infection with a Naturally Drug-Resistant Strain of Trypanosoma cruzi
Antimicrob. Agents Chemother. 1998 42: 2549-2556. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wiley A. Schell, Gisele Madeira Duboc De Almeida, Richard K. Dodge, Kenji Okonogi, and John R. Perfect

In Vitro and In Vivo Efficacy of the Triazole TAK-187 against Cryptococcus neoformans
Antimicrob. Agents Chemother. 1998 42: 2630-2632. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Irja Lutsar, Ian R. Friedland, Loretta Wubbel, Cynthia C. McCoig, Hasan S. Jafri, Winston Ng, Faryal Ghaffar, and George H. McCracken, Jr.

Pharmacodynamics of Gatifloxacin in Cerebrospinal Fluid in Experimental Cephalosporin-Resistant Pneumococcal Meningitis
Antimicrob. Agents Chemother. 1998 42: 2650-2655. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andy Oleksijew, Jon Meulbroek, Patty Ewing, Ken Jarvis, Mike Mitten, Lenette Paige, Ann Tovcimak, Mike Nukkula, Daniel Chu, and Jeffrey D. Alder

In Vivo Efficacy of ABT-255 against Drug-Sensitive and -Resistant Mycobacterium tuberculosis Strains
Antimicrob. Agents Chemother. 1998 42: 2674-2677. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Esther L. W. Barrow, Gary A. Winchester, Jay K. Staas, Debra C. Quenelle, and William W. Barrow

Use of Microsphere Technology for Targeted Delivery of Rifampin to Mycobacterium tuberculosis-Infected Macrophages
Antimicrob. Agents Chemother. 1998 42: 2682-2689. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey R. Aeschlimann, Marcus J. Zervos, and Michael J. Rybak

Treatment of Vancomycin-Resistant Enterococcus faecium with RP 59500 (Quinupristin-Dalfopristin) Administered by Intermittent or Continuous Infusion, Alone or in Combination with Doxycycline, in an In Vitro Pharmacodynamic Infection Model with Simulated Endocardial Vegetations
Antimicrob. Agents Chemother. 1998 42: 2710-2717. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cyrus J. Bacchi, Marcus Vargas, Donna Rattendi, Burt Goldberg, and Weicheng Zhou

Antitrypanosomal Activity of a New Triazine Derivative, SIPI 1029, In Vitro and in Model Infections
Antimicrob. Agents Chemother. 1998 42: 2718-2721. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. B. Mullen, A. J. Baillie, and K. C. Carter

Visceral Leishmaniasis in the BALB/c Mouse: A Comparison of the Efficacy of a Nonionic Surfactant Formulation of Sodium Stibogluconate with Those of Three Proprietary Formulations of Amphotericin B
Antimicrob. Agents Chemother. 1998 42: 2722-2725. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Sophie Dessus-Babus, Cécile M. Bébéar, Alain Charron, Christiane Bébéar, and Bertille de Barbeyrac

Sequencing of Gyrase and Topoisomerase IV Quinolone-Resistance-Determining Regions of Chlamydia trachomatis and Characterization of Quinolone-Resistant Mutants Obtained In Vitro
Antimicrob. Agents Chemother. 1998 42: 2474-2481. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marie-Cécile Ploy, Patrice Courvalin, and Thierry Lambert

Characterization of In40 of Enterobacter aerogenes BM2688, a Class 1 Integron with Two New Gene Cassettes, cmlA2 and qacF
Antimicrob. Agents Chemother. 1998 42: 2557-2563. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christian Therrien, Francois Sanschagrin, Timothy Palzkill, and Roger C. Levesque

Roles of Amino Acids 161 to 179 in the PSE-4  Loop in Substrate Specificity and in Resistance to Ceftazidime
Antimicrob. Agents Chemother. 1998 42: 2576-2583. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kieren A. Marr, Christopher N. Lyons, Tiger Rustad, Raleigh A. Bowden, and Theodore C. White

Rapid, Transient Fluconazole Resistance in Candida albicans Is Associated with Increased mRNA Levels of CDR
Antimicrob. Agents Chemother. 1998 42: 2584-2589. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hélène Aubry-Damon, Claude-James Soussy, and Patrice Courvalin

Characterization of Mutations in the rpoB Gene That Confer Rifampin Resistance in Staphylococcus aureus
Antimicrob. Agents Chemother. 1998 42: 2590-2594. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anne Gourmelen, Marie-Hélène Blondelet-Rouault, and Jean-Luc Pernodet

Characterization of a Glycosyl Transferase Inactivating Macrolides, Encoded by gimA from Streptomyces ambofaciens
Antimicrob. Agents Chemother. 1998 42: 2612-2619. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alison S. Orozco, Lindsey M. Higginbotham, Christopher A. Hitchcock, Tanya Parkinson, Derek Falconer, Ashraf S. Ibrahim, Mahmoud A. Ghannoum, and Scott G. Filler

Mechanism of Fluconazole Resistance in Candida krusei
Antimicrob. Agents Chemother. 1998 42: 2645-2649. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Linda M. Weigel, Christine D. Steward, and Fred C. Tenover

gyrA Mutations Associated with Fluoroquinolone Resistance in Eight Species of Enterobacteriaceae
Antimicrob. Agents Chemother. 1998 42: 2661-2667. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Y. J. Debets-Ossenkopp, A. B. Brinkman, E. J. Kuipers, C. M. J. E. Vandenbroucke-Grauls, and J. G. Kusters

Explaining the Bias in the 23S rRNA Gene Mutations Associated with Clarithromycin Resistance in Clinical Isolates of Helicobacter pylori
Antimicrob. Agents Chemother. 1998 42: 2749-2751. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric Rudant, Patrice Courvalin, and Thierry Lambert

Characterization of IS18, an Element Capable of Activating the Silent aac(6')-Ij Gene of Acinetobacter sp. 13 Strain BM2716 by Transposition
Antimicrob. Agents Chemother. 1998 42: 2759-2761. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joaquín Ruiz, Marco Sempere, Encarnación Simarro, and Asunción Fenoll

Description of Two New Isolates of Streptococcus pneumoniae in Spain That Are Highly Resistant to Cefotaxime
Antimicrob. Agents Chemother. 1998 42: 2768-2769. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Ammar Achour, Jean-Charles Landureau, Rosangela Salerno-Concalves, Jean-Claude Mazière, and Daniel Zagury

Restoration of Immune Response by a Cationic Amphiphilic Drug (AY 9944) In Vitro: A New Approach To Chemotherapy against Human Immunodeficiency Virus Type 1
Antimicrob. Agents Chemother. 1998 42: 2482-2491. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. K. Patick, M. Duran, Y. Cao, D. Shugarts, M. R. Keller, E. Mazabel, M. Knowles, S. Chapman, D. R. Kuritzkes, and M. Markowitz

Genotypic and Phenotypic Characterization of Human Immunodeficiency Virus Type 1 Variants Isolated from Patients Treated with the Protease Inhibitor Nelfinavir
Antimicrob. Agents Chemother. 1998 42: 2637-2644. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Maurizio Del Poeta, Wiley A. Schell, Christine C. Dykstra, Susan Jones, Richard R. Tidwell, Agnieszka Czarny, Miroslav Bajic, Marina Bajic, Arvind Kumar, David Boykin, and John R. Perfect

Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents
Antimicrob. Agents Chemother. 1998 42: 2495-2502. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maurizio Del Poeta, Wiley A. Schell, Christine C. Dykstra, Susan K. Jones, Richard R. Tidwell, Arvind Kumar, David W. Boykin, and John R. Perfect

In Vitro Antifungal Activities of a Series of Dication-Substituted Carbazoles, Furans, and Benzimidazoles
Antimicrob. Agents Chemother. 1998 42: 2503-2510. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter Lutwyche, Carol Cordeiro, David J. Wiseman, Maryse St-Louis, Mitchell Uh, Michael J. Hope, Murray S. Webb, and B. Brett Finlay

Intracellular Delivery and Antibacterial Activity of Gentamicin Encapsulated in pH-Sensitive Liposomes
Antimicrob. Agents Chemother. 1998 42: 2511-2520. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sung Yu Hong, Jong Eun Oh, Mi yun Kwon, Myeong Jun Choi, Ji Hye Lee, Bok Luel Lee, Hong Mo Moon, and Keun Hyeung Lee

Identification and Characterization of Novel Antimicrobial Decapeptides Generated by Combinatorial Chemistry
Antimicrob. Agents Chemother. 1998 42: 2534-2541. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aldona L. Baltch, Raymond P. Smith, William J. Ritz, and Lawrence H. Bopp

Comparison of Inhibitory and Bactericidal Activities and Postantibiotic Effects of LY333328 and Ampicillin Used Singly and in Combination against Vancomycin-Resistant Enterococcus faecium
Antimicrob. Agents Chemother. 1998 42: 2564-2568. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hui Wang, Robin Huebner, Minjun Chen, and Keith Klugman

Antibiotic Susceptibility Patterns of Streptococcus pneumoniae in China and Comparison of MICs by Agar Dilution and E-Test Methods
Antimicrob. Agents Chemother. 1998 42: 2633-2636. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kate Fortney, Patricia A. Totten, Robert I. Lehrer, and Stanley M. Spinola

Haemophilus ducreyi Is Susceptible to Protegrin
Antimicrob. Agents Chemother. 1998 42: 2690-2693. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karen L. Oakley, Caroline B. Moore, and David W. Denning

In Vitro Activity of the Echinocandin Antifungal Agent LY303,366 in Comparison with Itraconazole and Amphotericin B against Aspergillus spp.
Antimicrob. Agents Chemother. 1998 42: 2726-2730. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. Löwdin, I. Odenholt, and O. Cars

In Vitro Studies of Pharmacodynamic Properties of Vancomycin against Staphylococcus aureus and Staphylococcus epidermidis
Antimicrob. Agents Chemother. 1998 42: 2739-2744. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Achilleas Gikas, Ioanna Spyridaki, Anna Psaroulaki, Diamantis Kofterithis, and Yannis Tselentis

In Vitro Susceptibility of Coxiella burnetii to Trovafloxacin in Comparison with Susceptibilities to Pefloxacin, Ciprofloxacin, Ofloxacin, Doxycycline, and Clarithromycin
Antimicrob. Agents Chemother. 1998 42: 2747-2748. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. C. Struwig, P. L. Botha, and L. J. Chalkley

In Vitro Activities of 15 Antimicrobial Agents against Clinical Isolates of South African Enterococci
Antimicrob. Agents Chemother. 1998 42: 2752-2755. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jens Gieffers, Werner Solbach, and Matthias Maass

In Vitro Susceptibilities of Chlamydia pneumoniae Strains Recovered from Atherosclerotic Coronary Arteries
Antimicrob. Agents Chemother. 1998 42: 2762-2764. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter C. Fuchs, Arthur L. Barry, and Steven D. Brown

PMX-622 (Polymyxin B-Dextran 70) Does Not Alter In Vitro Activities of 11 Antimicrobial Agents
Antimicrob. Agents Chemother. 1998 42: 2765-2767. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Bernhard Jahn, Albert Rampp, Christian Dick, Andreas Jahn, Michael Palmer, and Sucharit Bhakdi

Accumulation of Amphotericin B in Human Macrophages Enhances Activity against Aspergillus fumigatus Conidia: Quantification of Conidial Kill at the Single-Cell Level
Antimicrob. Agents Chemother. 1998 42: 2569-2575. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nikolaos S. Soukos, Laurie Ann Ximenez-Fyvie, Michael R. Hamblin, Sigmund S. Socransky, and Tayyaba Hasan

Targeted Antimicrobial Photochemotherapy
Antimicrob. Agents Chemother. 1998 42: 2595-2601. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pedro Bonay, Isabel Durán-Chica, Manuel Fresno, Balbino Alarcón, and Antonio Alcina

Antiparasitic Effects of the Intra-Golgi Transport Inhibitor Megalomicin
Antimicrob. Agents Chemother. 1998 42: 2668-2673. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masaya Takei, Hideyuki Fukuda, Tokutaro Yasue, Masaki Hosaka, and Yasuo Oomori

Inhibitory Activities of Gatifloxacin (AM-1155), a Newly Developed Fluoroquinolone, against Bacterial and Mammalian Type II Topoisomerases
Antimicrob. Agents Chemother. 1998 42: 2678-2681. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laura Capa, Alfonso Mendoza, José L. Lavandera, Federico Gómez de las Heras, and José F. García-Bustos

Translation Elongation Factor 2 Is Part of the Target for a New Family of Antifungals
Antimicrob. Agents Chemother. 1998 42: 2694-2699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Soren M. Gantt, Joon Mo Myung, Marcelo R. S. Briones, Wei Dong Li, E. J. Corey, Satoshi Omura, Victor Nussenzweig, and Photini Sinnis

Proteasome Inhibitors Block Development of Plasmodium spp.
Antimicrob. Agents Chemother. 1998 42: 2731-2738. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mayumi Shimizu, Yasushi Shigeri, Yoshiro Tatsu, Susumu Yoshikawa, and Noboru Yumoto

Enhancement of Antimicrobial Activity of Neuropeptide Y by N-Terminal Truncation
Antimicrob. Agents Chemother. 1998 42: 2745-2746. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Klaus Stoeckel, Werner Hofheinz, Jean Paul Laneury, Patrick Duchene, Steve Shedlofsky, and Robert A. Blouin

Stability of Cephalosporin Prodrug Esters in Human Intestinal Juice: Implications for Oral Bioavailability
Antimicrob. Agents Chemother. 1998 42: 2602-2606. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Estelle Cormet-Boyaka, Jean-François Huneau, Agnès Mordrelle, Prosper N. Boyaka, Claude Carbon, Ethan Rubinstein, and Daniel Tomé

Secretion of Sparfloxacin from the Human Intestinal Caco-2 Cell Line Is Altered by P-Glycoprotein Inhibitors
Antimicrob. Agents Chemother. 1998 42: 2607-2611. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thomas Mindermann, Werner Zimmerli, and Otmar Gratzl

Rifampin Concentrations in Various Compartments of the Human Brain: A Novel Method for Determining Drug Levels in the Cerebral Extracellular Space
Antimicrob. Agents Chemother. 1998 42: 2626-2629. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian L. Robbins, Thu T. Tran, Frank H. Pinkerton, Jr., Fatima Akeb, Roger Guedj, Jacques Grassi, Danny Lancaster, and Arnold Fridland

Development of a New Cartridge Radioimmunoassay for Determination of Intracellular Levels of Lamivudine Triphosphate in the Peripheral Blood Mononuclear Cells of Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 1998 42: 2656-2660. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andreas H. Groll, Tin Sein, Vidas Petraitis, Ruta Petraitiene, Diana Callender, Corina E. Gonzalez, Neelam Giri, John Bacher, Stephen Piscitelli, and Thomas J. Walsh

Compartmental Pharmacokinetics and Tissue Drug Distribution of the Pradimicin Derivative BMS 181184 in Rabbits
Antimicrob. Agents Chemother. 1998 42: 2700-2705. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susan M. Abdel-Rahman and Gregory L. Kearns

Single-Dose Pharmacokinetics of a Pleconaril (VP63843) Oral Solution and Effect of Food
Antimicrob. Agents Chemother. 1998 42: 2706-2709. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annie Delon, Claudine Pariat, Philippe Courtois, Serge Bouquet, and William Couet

A New Approach for Early Assessment of the Epileptogenic Potential of Quinolones
Antimicrob. Agents Chemother. 1998 42: 2756-2758. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

Jianghai Wang, Jan Neuhard, and Staffan Eriksson

An Escherichia coli System Expressing Human Deoxyribonucleoside Salvage Enzymes for Evaluation of Potential Antiproliferative Nucleoside Analogs
Antimicrob. Agents Chemother. 1998 42: 2620-2625. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Jean-François Magnaval

Apparent Weak Efficacy of Ivermectin for Treatment of Human Toxocariasis
Antimicrob. Agents Chemother. 1998 42: 2770. [Full Text] [PDF] [Reprints and Permissions]  

Roger Labia, El Bachir Chaibi, Danielle Sirot, Catherine Chanal-Claris, Paul Stapleton, Kevin Shannon, and Gary French

Inhibitor-Resistant TEM -Lactamases: Revision of the TEM-41 Sequence
Antimicrob. Agents Chemother. 1998 42: 2771. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Luis Martínez-Martínez, Isabel García, Sofía Ballesta, Vicente Javier Benedí, Santiago Hernández-Allés, and Alvaro Pascual

Energy-Dependent Accumulation of Fluoroquinolones in Quinolone-Resistant Klebsiella pneumoniae Strains
Antimicrob. Agents Chemother. 1998 42: 2772. [Full Text] [PDF] [Reprints and Permissions]  

Author's Correction:

Paul Stapleton, Pei-Jun Wu, Anna King, Kevin Shannon, Gary French, and Ian Phillips

Incidence and Mechanisms of Resistance to the Combination of Amoxicillin and Clavulanic Acid in Escherichia coli
Antimicrob. Agents Chemother. 1998 42: 2773. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.