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Minireviews:

John Samuelson

Why Metronidazole Is Active against both Bacteria and Parasites
Antimicrob. Agents Chemother. 1999 43: 1533-1541. [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Carol Friedrich, Monisha G. Scott, Nedra Karunaratne, Hong Yan, and Robert E. W. Hancock

Salt-Resistant Alpha-Helical Cationic Antimicrobial Peptides
Antimicrob. Agents Chemother. 1999 43: 1542-1548. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Pratten and M. Wilson

Antimicrobial Susceptibility and Composition of Microcosm Dental Plaques Supplemented with Sucrose
Antimicrob. Agents Chemother. 1999 43: 1595-1599. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sung Yu Hong, Jong Eun Oh, and Keun Hyeung Lee

In Vitro Antifungal Activity and Cytotoxicity of a Novel Membrane-Active Peptide
Antimicrob. Agents Chemother. 1999 43: 1704-1707. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Akira Watanabe, Yutaka Tokue, Hiroshi Takahashi, Tohru Kikuchi, Takao Kobayashi, Kazunori Gomi, Shigeru Fujimura, and Toshihiro Nukiwa

In Vitro Activity of HSR-903, a New Oral Quinolone, against Bacteria Causing Respiratory Infections
Antimicrob. Agents Chemother. 1999 43: 1767-1768. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lisa L. Dever, Christine V. Torigian, and Alan G. Barbour

In Vitro Activities of the Everninomicin SCH 27899 and Other Newer Antimicrobial Agents against Borrelia burgdorferi
Antimicrob. Agents Chemother. 1999 43: 1773-1775. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anis A. Khan, Fausto G. Araujo, Katherine E. Brighty, Thomas D. Gootz, and Jack S. Remington

Anti-Toxoplasma gondii Activities and Structure-Activity Relationships of Novel Fluoroquinolones Related to Trovafloxacin
Antimicrob. Agents Chemother. 1999 43: 1783-1787. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katsuhiro Mabe, Masami Yamada, Itaro Oguni, and Tsuneo Takahashi

In Vitro and In Vivo Activities of Tea Catechins against Helicobacter pylori
Antimicrob. Agents Chemother. 1999 43: 1788-1791. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Heike M. Freidank, Philipp Losch, Heike Vögele, and Margit Wiedmann-Al-Ahmad

In Vitro Susceptibilities of Chlamydia pneumoniae Isolates from German Patients and Synergistic Activity of Antibiotic Combinations
Antimicrob. Agents Chemother. 1999 43: 1808-1810. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Michael J. Rybak, Betty J. Abate, S. Lena Kang, Michael J. Ruffing, Stephen A. Lerner, and George L. Drusano

Prospective Evaluation of the Effect of an Aminoglycoside Dosing Regimen on Rates of Observed Nephrotoxicity and Ototoxicity
Antimicrob. Agents Chemother. 1999 43: 1549-1555. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Teresita Mazzei, Calogero Surrenti, Andrea Novelli, Maria Rosa Biagini, Stefania Fallani, Maria Iris Cassetta, Silvia Conti, and Elisabetta Surrenti

Pharmacokinetics of Dirithromycin in Patients with Mild or Moderate Cirrhosis
Antimicrob. Agents Chemother. 1999 43: 1556-1559. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alasdair P. MacGowan, Karen E. Bowker, Mandy Wootton, and H. Alan Holt

Activity of Moxifloxacin, Administered Once a Day, against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model of Infection
Antimicrob. Agents Chemother. 1999 43: 1560-1564. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurene H. Wang, Gregory E. Chittick, and James A. McDowell

Single-Dose Pharmacokinetics and Safety of Abacavir (1592U89), Zidovudine, and Lamivudine Administered Alone and in Combination in Adults with Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 1999 43: 1708-1715. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. De Sarro, V. Cecchetti, V. Fravolini, F. Naccari, O. Tabarrini, and G. De Sarro

Effects of Novel 6-Desfluoroquinolones and Classic Quinolones on Pentylenetetrazole-Induced Seizures in Mice
Antimicrob. Agents Chemother. 1999 43: 1729-1736. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. M. H. Gómez, J. J. Cordingly, and M. G. A. Palazzo

Altered Pharmacokinetics of Ceftazidime in Critically Ill Patients
Antimicrob. Agents Chemother. 1999 43: 1798-1802. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

S. Pelzer, R. Süßmuth, D. Heckmann, J. Recktenwald, P. Huber, G. Jung, and W. Wohlleben

Identification and Analysis of the Balhimycin Biosynthetic Gene Cluster and Its Use for Manipulating Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908
Antimicrob. Agents Chemother. 1999 43: 1565-1573. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anton J. Woo, William R. Strohl, and Nigel D. Priestley

Nonactin Biosynthesis: the Product of nonS Catalyzes the Formation of the Furan Ring of Nonactic Acid
Antimicrob. Agents Chemother. 1999 43: 1662-1668. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Anne Y. C. Saiki, Linus L. Shen, Chih-Ming Chen, John Baranowski, and Claude G. Lerner

DNA Cleavage Activities of Staphylococcus aureus Gyrase and Topoisomerase IV Stimulated by Quinolones and 2-Pyridones
Antimicrob. Agents Chemother. 1999 43: 1574-1577. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jamese J. Hilliard, Raul M. Goldschmidt, Lisa Licata, Ellen Z. Baum, and Karen Bush

Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems
Antimicrob. Agents Chemother. 1999 43: 1693-1699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert J. Deschenes, Hong Lin, Addison D. Ault, and Jan S. Fassler

Antifungal Properties and Target Evaluation of Three Putative Bacterial Histidine Kinase Inhibitors
Antimicrob. Agents Chemother. 1999 43: 1700-1703. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David C. Lamb, Segula Maspahy, Diane E. Kelly, Nigel J. Manning, Antonia Geber, John E. Bennett, and Steven L. Kelly

Purification, Reconstitution, and Inhibition of Cytochrome P-450 Sterol ²²-Desaturase from the Pathogenic Fungus Candida glabrata
Antimicrob. Agents Chemother. 1999 43: 1725-1728. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Hitoshi Komatsuzawa, Gil H. Choi, Kouji Ohta, Motoyuki Sugai, Monique T. Tran, and Hidekazu Suginaka

Cloning and Characterization of a Gene, pbpF, Encoding a New Penicillin-Binding Protein, PBP2B, in Staphylococcus aureus
Antimicrob. Agents Chemother. 1999 43: 1578-1583. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laura Lauretti, Maria Letizia Riccio, Annarita Mazzariol, Giuseppe Cornaglia, Gianfranco Amicosante, Roberta Fontana, and Gian Maria Rossolini

Cloning and Characterization of bla_VIM, a New Integron-Borne Metallo--Lactamase Gene from a Pseudomonas aeruginosa Clinical Isolate
Antimicrob. Agents Chemother. 1999 43: 1584-1590. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Nyfors, E. Könönen, A. Takala, and H. Jousimies-Somer

-Lactamase Production by Oral Anaerobic Gram-Negative Species in Infants in Relation to Previous Antimicrobial Therapy
Antimicrob. Agents Chemother. 1999 43: 1591-1594. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jose L. Lopez-Ribot, Robert K. McAtee, Sofia Perea, William R. Kirkpatrick, Michael G. Rinaldi, and Thomas F. Patterson

Multiple Resistant Phenotypes of Candida albicans Coexist during Episodes of Oropharyngeal Candidiasis in Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 1999 43: 1621-1630. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Donald T. Dubin, Joseph E. Fitzgibbon, Massoumeh D. Nahvi, and Joseph F. John

Topoisomerase Sequences of Coagulase-Negative Staphylococcal Isolates Resistant to Ciprofloxacin or Trovafloxacin
Antimicrob. Agents Chemother. 1999 43: 1631-1637. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frederic Laurent, Laurent Poirel, Thierry Naas, El Bachir Chaibi, Roger Labia, Patrick Boiron, and Patrice Nordmann

Biochemical-Genetic Analysis and Distribution of FAR-1, a Class A -Lactamase from Nocardia farcinica
Antimicrob. Agents Chemother. 1999 43: 1644-1650. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. Bermudes, F. Jude, E. B. Chaibi, C. Arpin, C. Bebear, R. Labia, and C. Quentin

Molecular Characterization of TEM-59 (IRT-17), a Novel Inhibitor-Resistant TEM-Derived -Lactamase in a Clinical Isolate of Klebsiella oxytoca
Antimicrob. Agents Chemother. 1999 43: 1657-1661. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis Martínez-Martínez, Alvaro Pascual, Santiago Hernández-Allés, Dolores Alvarez-Díaz, Ana Isabel Suárez, John Tran, Vicente Javier Benedí, and George A. Jacoby

Roles of -Lactamases and Porins in Activities of Carbapenems and Cephalosporins against Klebsiella pneumoniae
Antimicrob. Agents Chemother. 1999 43: 1669-1673. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christiane Werckenthin, Stefan Schwarz, and Henrik Westh

Structural Alterations in the Translational Attenuator of Constitutively Expressed ermC Genes
Antimicrob. Agents Chemother. 1999 43: 1681-1685. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark L. Nelson and Stuart B. Levy

Reversal of Tetracycline Resistance Mediated by Different Bacterial Tetracycline Resistance Determinants by an Inhibitor of the Tet(B) Antiport Protein
Antimicrob. Agents Chemother. 1999 43: 1719-1724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alexey Bulychev and Shahriar Mobashery

Class C -Lactamases Operate at the Diffusion Limit for Turnover of Their Preferred Cephalosporin Substrates
Antimicrob. Agents Chemother. 1999 43: 1743-1746. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yuzhi Dong, Xilin Zhao, John Domagala, and Karl Drlica

Effect of Fluoroquinolone Concentration on Selection of Resistant Mutants of Mycobacterium bovis BCG and Staphylococcus aureus
Antimicrob. Agents Chemother. 1999 43: 1756-1758. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George A. Jacoby and John Tran

Sequence of the MIR-1 -Lactamase Gene
Antimicrob. Agents Chemother. 1999 43: 1759-1760. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nadine Lemaitre, Wladimir Sougakoff, Chantal Truffot-Pernot, and Vincent Jarlier

Characterization of New Mutations in Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Identification of Conserved Regions Important for the Catalytic Activity of the Pyrazinamidase PncA
Antimicrob. Agents Chemother. 1999 43: 1761-1763. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Harri J. Marttila, Merja Marjamäki, Elena Vyshnevskaya, Boris I. Vyshnevskiy, Tatjana F. Otten, Alexandr V. Vasilyef, and Matti K. Viljanen

pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates from Northwestern Russia
Antimicrob. Agents Chemother. 1999 43: 1764-1766. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David R. Macinga, Michael R. Paradise, Milica M. Parojcic, and Philip N. Rather

Activation of the 2'-N-Acetyltransferase Gene [aac(2')-Ia] in Providencia stuartii by an Interaction of AarP with the Promoter Region
Antimicrob. Agents Chemother. 1999 43: 1769-1772. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Leen-Jan van Doorn, Yvette J. Debets-Ossenkopp, Armelle Marais, Ricardo Sanna, Francis Mégraud, Johannes G. Kusters, and Wim G. V. Quint

Rapid Detection, by PCR and Reverse Hybridization, of Mutations in the Helicobacter pylori 23S rRNA Gene, Associated with Macrolide Resistance
Antimicrob. Agents Chemother. 1999 43: 1779-1782. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shu-Fen Weng, Chun-Yi Chen, Yeong-Sheng Lee, Juey-Wen Lin, and Yi-Hsiung Tseng

Identification of a Novel -Lactamase Produced by Xanthomonas campestris, a Phytopathogenic Bacterium
Antimicrob. Agents Chemother. 1999 43: 1792-1797. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria P. Dore, David Y. Graham, Antonia R. Sepulveda, Giuseppe Realdi, and Michael S. Osato

Sensitivity of Amoxicillin-Resistant Helicobacter pylori to Other Penicillins
Antimicrob. Agents Chemother. 1999 43: 1803-1804. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Patricia A. Cane, Pamela Cook, Daina Ratcliffe, David Mutimer, and Deenan Pillay

Use of Real-Time PCR and Fluorimetry To Detect Lamivudine Resistance-Associated Mutations in Hepatitis B Virus
Antimicrob. Agents Chemother. 1999 43: 1600-1608. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David P. Calfee, Amy W. Peng, Lindsey M. Cass, Monica Lobo, and Frederick G. Hayden

Safety and Efficacy of Intravenous Zanamivir in Preventing Experimental Human Influenza A Virus Infection
Antimicrob. Agents Chemother. 1999 43: 1616-1620. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rodrigo Brindeiro, Bart Vanderborght, Elena Caride, Letícia Correa, Rejane M. Oravec, Oscar Berro, Lieven Stuyver, and Amilcar Tanuri

Sequence Diversity of the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 from Untreated Brazilian Individuals
Antimicrob. Agents Chemother. 1999 43: 1674-1680. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian M. Sadler, Cynthia D. Hanson, Gregory E. Chittick, William T. Symonds, and Neil S. Roskell

Safety and Pharmacokinetics of Amprenavir (141W94), a Human Immunodeficiency Virus (HIV) Type 1 Protease Inhibitor, following Oral Administration of Single Doses to HIV-Infected Adults
Antimicrob. Agents Chemother. 1999 43: 1686-1692. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Nazir A. Barekzi, Kornelis A. Poelstra, Adrian G. Felts, Ignacio A. Rojas, Jeffrey B. Slunt, and David W. Grainger

Efficacy of Locally Delivered Polyclonal Immunoglobulin against Pseudomonas aeruginosa Peritonitis in a Murine Model
Antimicrob. Agents Chemother. 1999 43: 1609-1615. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Linda B. Adams, Indu Sinha, Scott G. Franzblau, James L. Krahenbuhl, and Reeta T. Mehta

Effective Treatment of Acute and Chronic Murine Tuberculosis with Liposome-Encapsulated Clofazimine
Antimicrob. Agents Chemother. 1999 43: 1638-1643. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christian Michelet, Stephen L. Leib, Daniele Bentue-Ferrer, and Martin G. Täuber

Comparative Efficacies of Antibiotics in a Rat Model of Meningoencephalitis Due to Listeria monocytogenes
Antimicrob. Agents Chemother. 1999 43: 1651-1656. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John R. Graybill, Laura Najvar, Annette Fothergill, Rosie Bocanegra, and Federico Gomez de las Heras

Activities of Sordarins in Murine Histoplasmosis
Antimicrob. Agents Chemother. 1999 43: 1716-1718. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan-Qiong Xiong, Leon Iri Kupferwasser, Philip M. Zack, and Arnold S. Bayer

Comparative Efficacies of Liposomal Amikacin (MiKasome) plus Oxacillin versus Conventional Amikacin plus Oxacillin in Experimental Endocarditis Induced by Staphylococcus aureus: Microbiological and Echocardiographic Analyses
Antimicrob. Agents Chemother. 1999 43: 1737-1742. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael W. Climo, Roberto L. Patron, and Gordon L. Archer

Combinations of Vancomycin and -Lactams Are Synergistic against Staphylococci with Reduced Susceptibilities to Vancomycin
Antimicrob. Agents Chemother. 1999 43: 1747-1753. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Roberto L. Patron, Michael W. Climo, Beth P. Goldstein, and Gordon L. Archer

Lysostaphin Treatment of Experimental Aortic Valve Endocarditis Caused by a Staphylococcus aureus Isolate with Reduced Susceptibility to Vancomycin
Antimicrob. Agents Chemother. 1999 43: 1754-1755. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eduardo Caio Torres-Santos, José M. Rodrigues, Jr., Davyson L. Moreira, Maria Auxiliadora C. Kaplan, and Bartira Rossi-Bergmann

Improvement of In Vitro and In Vivo Antileishmanial Activities of 2',6'-Dihydroxy-4'-Methoxychalcone by Entrapment in Poly(D,L-Lactide) Nanoparticles
Antimicrob. Agents Chemother. 1999 43: 1776-1778. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Irja Lutsar, Ian R. Friedland, Hasan S. Jafri, Loretta Wubbel, Winston Ng, Faryal Ghaffar, and George H. McCracken, Jr.

Efficacy of Gatifloxacin in Experimental Escherichia coli Meningitis
Antimicrob. Agents Chemother. 1999 43: 1805-1807. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Rie Ohta, Norihiko Yamada, Hisae Kaneko, Keiko Ishikawa, Hiroyuki Fukuda, Tsuchiyoshi Fujino, and Atsushi Suzuki

In Vitro Inhibition of the Growth of Helicobacter pylori by Oil-Macerated Garlic Constituents
Antimicrob. Agents Chemother. 1999 43: 1811-1812. [Full Text] [PDF] [Reprints and Permissions]  

G. Werner and W. Witte

Characterization of a New Enterococcal Gene, satG, Encoding a Putative Acetyltransferase Conferring Resistance to Streptogramin A Compounds
Antimicrob. Agents Chemother. 1999 43: 1813-1814. [Full Text] [PDF] [Reprints and Permissions]  

S. Eralp Bellibas;, Daniele Ouellet, and Ann Hsu

Ritonavir-Fluoxetine Interaction
Antimicrob. Agents Chemother. 1999 43: 1815. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.