To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Mechanisms of Resistance:

Kristen N. Schurek, Alexandra K. Marr, Patrick K. Taylor, Irith Wiegand, Lucie Semenec, Bhavjinder K. Khaira, and Robert E. W. Hancock

Novel Genetic Determinants of Low-Level Aminoglycoside Resistance in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2008 52: 4213-4219. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Céline Barnadas, Arsène Ratsimbasoa, Magali Tichit, Christiane Bouchier, Martial Jahevitra, Stéphane Picot, and Didier Ménard

Plasmodium vivax Resistance to Chloroquine in Madagascar: Clinical Efficacy and Polymorphisms in pvmdr1 and pvcrt-o Genes
Antimicrob. Agents Chemother. 2008 52: 4233-4240. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Noriyuki Nagano, Yukiko Nagano, Kouji Kimura, Kiyoko Tamai, Hideji Yanagisawa, and Yoshichika Arakawa

Genetic Heterogeneity in pbp Genes among Clinically Isolated Group B Streptococci with Reduced Penicillin Susceptibility
Antimicrob. Agents Chemother. 2008 52: 4258-4267. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hong Yang, Hongbin Chen, Qiwen Yang, Minjun Chen, and Hui Wang

High Prevalence of Plasmid-Mediated Quinolone Resistance Genes qnr and aac(6')-Ib-cr in Clinical Isolates of Enterobacteriaceae from Nine Teaching Hospitals in China
Antimicrob. Agents Chemother. 2008 52: 4268-4273. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sabrina Schubert, P. David Rogers, and Joachim Morschhäuser

Gain-of-Function Mutations in the Transcription Factor MRR1 Are Responsible for Overexpression of the MDR1 Efflux Pump in Fluconazole-Resistant Candida dubliniensis Strains
Antimicrob. Agents Chemother. 2008 52: 4274-4280. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Ilana Lopes Baratella da Cunha Camargo, Hui-Min Neoh, Longzhu Cui, and Keiichi Hiramatsu

Serial Daptomycin Selection Generates Daptomycin-Nonsusceptible Staphylococcus aureus Strains with a Heterogeneous Vancomycin-Intermediate Phenotype
Antimicrob. Agents Chemother. 2008 52: 4289-4299. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adele M. Lehane and Kiaran Kirk

Chloroquine Resistance-Conferring Mutations in pfcrt Give Rise to a Chloroquine-Associated H⁺ Leak from the Malaria Parasite's Digestive Vacuole
Antimicrob. Agents Chemother. 2008 52: 4374-4380. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anna C. Shore, Angela S. Rossney, Brian O'Connell, Celine M. Herra, Derek J. Sullivan, Hilary Humphreys, and David C. Coleman

Detection of Staphylococcal Cassette Chromosome mec-Associated DNA Segments in Multiresistant Methicillin-Susceptible Staphylococcus aureus (MSSA) and Identification of Staphylococcus epidermidis ccrAB4 in both Methicillin-Resistant S. aureus and MSSA
Antimicrob. Agents Chemother. 2008 52: 4407-4419. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sebastien Fraud, Aaron J. Campigotto, Zhilin Chen, and Keith Poole

MexCD-OprJ Multidrug Efflux System of Pseudomonas aeruginosa: Involvement in Chlorhexidine Resistance and Induction by Membrane-Damaging Agents Dependent upon the AlgU Stress Response Sigma Factor
Antimicrob. Agents Chemother. 2008 52: 4478-4482. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elena B. M. Breidenstein, Bhavjinder K. Khaira, Irith Wiegand, Joerg Overhage, and Robert E. W. Hancock

Complex Ciprofloxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility
Antimicrob. Agents Chemother. 2008 52: 4486-4491. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Diego A. Goyeneche-Patino, Liliana Valderrama, John Walker, and Nancy G. Saravia

Antimony Resistance and Trypanothione in Experimentally Selected and Clinical Strains of Leishmania panamensis
Antimicrob. Agents Chemother. 2008 52: 4503-4506. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel R. Gentry, Lynn McCloskey, Michael N. Gwynn, Stephen F. Rittenhouse, Nicole Scangarella, Ribhi Shawar, and David J. Holmes

Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 4507-4509. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ana Herrero, M. Carmen Mendoza, Rosaura Rodicio, and M. Rosario Rodicio

Characterization of pUO-StVR2, a Virulence-Resistance Plasmid Evolved from the pSLT Virulence Plasmid of Salmonella enterica Serovar Typhimurium
Antimicrob. Agents Chemother. 2008 52: 4514-4517. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mindy G. Brown, Elizabeth H. Mitchell, and David L. Balkwill

Tet 42, a Novel Tetracycline Resistance Determinant Isolated from Deep Terrestrial Subsurface Bacteria
Antimicrob. Agents Chemother. 2008 52: 4518-4521. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Poonam Gautam, Jata Shankar, Taruna Madan, Ravi Sirdeshmukh, Curam Sreenivasacharlu Sundaram, Wasudev Namdeo Gade, Seemi Farhat Basir, and Puranam Usha Sarma

Proteomic and Transcriptomic Analysis of Aspergillus fumigatus on Exposure to Amphotericin B
Antimicrob. Agents Chemother. 2008 52: 4220-4227. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Ian M. Gut, Angela M. Prouty, Jimmy D. Ballard, Wilfred A. van der Donk, and Steven R. Blanke

Inhibition of Bacillus anthracis Spore Outgrowth by Nisin
Antimicrob. Agents Chemother. 2008 52: 4281-4288. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hadar Sarig, Shahar Rotem, Lior Ziserman, Dganit Danino, and Amram Mor

Impact of Self-Assembly Properties on Antibacterial Activity of Short Acyl-Lysine Oligomers
Antimicrob. Agents Chemother. 2008 52: 4308-4314. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Matt S. Anderson, Thomas N. Kakuda, William Hanley, Jutta Miller, James T. Kost, Randall Stoltz, Larissa A. Wenning, Julie A. Stone, Richard M. W. Hoetelmans, John A. Wagner, and Marian Iwamoto

Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Healthy Subjects
Antimicrob. Agents Chemother. 2008 52: 4228-4232. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Selwyn J. Hurwitz, Ghazia Asif, Nancy M. Kivel, and Raymond F. Schinazi

Development of an Optimized Dose for Coformulation of Zidovudine with Drugs That Select for the K65R Mutation Using a Population Pharmacokinetic and Enzyme Kinetic Simulation Model
Antimicrob. Agents Chemother. 2008 52: 4241-4250. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fenglei Huang, Michael Koenen-Bergmann, Thomas R. MacGregor, Arne Ring, Susan Hattox, and Patrick Robinson

Pharmacokinetic and Safety Evaluation of BILR 355, a Second-Generation Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy Volunteers
Antimicrob. Agents Chemother. 2008 52: 4300-4307. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marian Iwamoto, Larissa A. Wenning, Amelia S. Petry, Martine Laethem, Marina De Smet, James T. Kost, Sheila A. Breidinger, Eric C. Mangin, Neal Azrolan, Howard E. Greenberg, Wouter Haazen, Julie A. Stone, Keith M. Gottesdiener, and John A. Wagner

Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir
Antimicrob. Agents Chemother. 2008 52: 4338-4343. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Benjamin J. Cairns and Robert J. H. Payne

Bacteriophage Therapy and the Mutant Selection Window
Antimicrob. Agents Chemother. 2008 52: 4344-4350. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tsin W. Yeo, Indri Rooslamiati, Retno Gitawati, Emiliana Tjitra, Daniel A. Lampah, Enny Kenangalem, Yvette R. McNeil, Richard N. Price, Nicholas M. Anstey, and Stephen B. Duffull

Pharmacokinetics of L-Arginine in Adults with Moderately Severe Malaria
Antimicrob. Agents Chemother. 2008 52: 4381-4387. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Anne-Geneviève Marcelin, Philippe Flandre, Jean-Michel Molina, Christine Katlama, Patrick Yeni, Francois Raffi, Zeina Antoun, Mounir Ait-Khaled, and Vincent Calvez

Genotypic Resistance Analysis of the Virological Response to Fosamprenavir-Ritonavir in Protease Inhibitor-Experienced Patients in CONTEXT and TRIAD Clinical Trials
Antimicrob. Agents Chemother. 2008 52: 4251-4257. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edwin DeJesus, Michael S. Gottlieb, Joseph C. Gathe, Jr., Michael L. Greenberg, Carol Jean Guittari, and Andrew R. Zolopa

Safety and Efficacy of Enfuvirtide in Combination with Darunavir-Ritonavir and an Optimized Background Regimen in Treatment-Experienced Human Immunodeficiency Virus-Infected Patients: the Below the Level of Quantification Study
Antimicrob. Agents Chemother. 2008 52: 4315-4319. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dong Yu, Mallikarjuna R. Putta, Lakshmi Bhagat, Meiru Dai, Daqing Wang, Anthony F. Trombino, Tim Sullivan, Ekambar R. Kandimalla, and Sudhir Agrawal

Impact of Secondary Structure of Toll-Like Receptor 9 Agonists on Interferon Alpha Induction
Antimicrob. Agents Chemother. 2008 52: 4320-4325. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark N. Prichard, Caroll B. Hartline, Emma A. Harden, Shannon L. Daily, James R. Beadle, Nadejda Valiaeva, Earl R. Kern, and Karl Y. Hostetler

Inhibition of Herpesvirus Replication by Hexadecyloxypropyl Esters of Purine- and Pyrimidine-Based Phosphonomethoxyethyl Nucleoside Phosphonates
Antimicrob. Agents Chemother. 2008 52: 4326-4330. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Giorgio Conti, Walter Magliani, Stefania Conti, Lucia Nencioni, Rossella Sgarbanti, Anna Teresa Palamara, and Luciano Polonelli

Therapeutic Activity of an Anti-Idiotypic Antibody-Derived Killer Peptide against Influenza A Virus Experimental Infection
Antimicrob. Agents Chemother. 2008 52: 4331-4337. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samir Ali, Vincent Leveque, Sophie Le Pogam, Han Ma, Friederike Philipp, Nicole Inocencio, Mark Smith, Andre Alker, Hyunsoon Kang, Isabel Najera, Klaus Klumpp, Julian Symons, Nick Cammack, and Wen-Rong Jiang

Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479
Antimicrob. Agents Chemother. 2008 52: 4356-4369. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, Carlo W. Boutton, Ludo Quirynen, Tania Ivens, Liesbet van der Helm, Geneviève Vandercruyssen, Wendy Mostmans, Frédéric Delouvroy, Pascale Dehertogh, Maxwell D. Cummings, Jean-Francois Bonfanti, Kenneth A. Simmen, and Pierre Raboisson

1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors
Antimicrob. Agents Chemother. 2008 52: 4420-4431. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Scott D. Seiwert, Steven W. Andrews, Yutong Jiang, Vladimir Serebryany, Hua Tan, Karl Kossen, P. T. Ravi Rajagopalan, Shawn Misialek, Sarah K. Stevens, Antitsa Stoycheva, Jin Hong, Sharlene R. Lim, Xiaoli Qin, Robert Rieger, Kevin R. Condroski, Hailong Zhang, Mary Geck Do, Christine Lemieux, Gary P. Hingorani, Dylan P. Hartley, John A. Josey, Lin Pan, Leonid Beigelman, and Lawrence M. Blatt

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)
Antimicrob. Agents Chemother. 2008 52: 4432-4441. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Patrick M. Schlievert, Kristi L. Strandberg, Amanda J. Brosnahan, Marnie L. Peterson, Stefan E. Pambuccian, Karla R. Nephew, Kevin G. Brunner, Nancy J. Schultz-Darken, and Ashley T. Haase

Glycerol Monolaurate Does Not Alter Rhesus Macaque (Macaca mulatta) Vaginal Lactobacilli and Is Safe for Chronic Use
Antimicrob. Agents Chemother. 2008 52: 4448-4454. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Waléria-Aleixo, A. N. Martins, M. B. Arruda, R. M. Brindeiro, R. M. Da-Silva, F. F. Nobre, D. B. Greco, and A. Tanuri

Drug Resistance Mutation Profile and Accumulation Kinetics in Human Immunodeficiency Virus-Positive Individuals Infected with Subtypes B and F Failing Highly Active Antiretroviral Therapy Are Influenced by Different Viral Codon Usage Patterns
Antimicrob. Agents Chemother. 2008 52: 4497-4502. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Oscar Cirioni, Roberto Ghiselli, Carmela Silvestri, Wojciech Kamysz, Fiorenza Orlando, Alessandra Riva, Elzbieta Kamysz, Sefora Castelletti, Marco Rocchi, Vittorio Saba, Giorgio Scalise, and Andrea Giacometti

Efficacy of the Combination of Tachyplesin III and Clarithromycin in Rat Models of Escherichia coli Sepsis
Antimicrob. Agents Chemother. 2008 52: 4351-4355. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karen E. Bowker, Alan R. Noel, and Alasdair P. MacGowan

Pharmacodynamics of Minocycline against Staphylococcus aureus in an In Vitro Pharmacokinetic Model
Antimicrob. Agents Chemother. 2008 52: 4370-4373. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paul E. Verweij, Debbie T. A. Te Dorsthorst, Willem H. P. Janssen, Jacques F. G. M. Meis, and Johan W. Mouton

In Vitro Activities at pH 5.0 and pH 7.0 and In Vivo Efficacy of Flucytosine against Aspergillus fumigatus
Antimicrob. Agents Chemother. 2008 52: 4483-4485. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia M. Tavares, Karin Thevissen, Bruno P. A. Cammue, Isabelle E. J. A. François, Eliana Barreto-Bergter, Carlos P. Taborda, Alexandre F. Marques, Marcio L. Rodrigues, and Leonardo Nimrichter

In Vitro Activity of the Antifungal Plant Defensin RsAFP2 against Candida Isolates and Its In Vivo Efficacy in Prophylactic Murine Models of Candidiasis
Antimicrob. Agents Chemother. 2008 52: 4522-4525. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Chris M. Pillar, Mohana K. Torres, Nina P. Brown, Dineshchandra Shah, and Daniel F. Sahm

In Vitro Activity of Doripenem, a Carbapenem for the Treatment of Challenging Infections Caused by Gram-Negative Bacteria, against Recent Clinical Isolates from the United States
Antimicrob. Agents Chemother. 2008 52: 4388-4399. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

K. J. Shaw, S. Poppe, R. Schaadt, V. Brown-Driver, J. Finn, C. M. Pillar, D. Shinabarger, and G. Zurenko

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains
Antimicrob. Agents Chemother. 2008 52: 4442-4447. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bogdana Krivogorsky, Peter Grundt, Robert Yolken, and Lorraine Jones-Brando

Inhibition of Toxoplasma gondii by Indirubin and Tryptanthrin Analogs
Antimicrob. Agents Chemother. 2008 52: 4466-4469. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christiane Gaudreau, Yves Girouard, Huguette Gilbert, Josée Gagnon, and Sadjia Bekal

Comparison of Disk Diffusion and Agar Dilution Methods for Erythromycin, Ciprofloxacin, and Tetracycline Susceptibility Testing of Campylobacter coli and for Tetracycline Susceptibility Testing of Campylobacter jejuni subsp. jejuni
Antimicrob. Agents Chemother. 2008 52: 4475-4477. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David R. Snydman, Nilda V. Jacobus, and Laura A. McDermott

In Vitro Activities of Doripenem, a New Broad-Spectrum Carbapenem, against Recently Collected Clinical Anaerobic Isolates, with Emphasis on the Bacteroides fragilis Group
Antimicrob. Agents Chemother. 2008 52: 4492-4496. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Klaudia Kosowska-Shick, Lois M. Ednie, Pamela McGhee, Kathy Smith, Cynthia D. Todd, Amanda Wehler, and Peter C. Appelbaum

Incidence and Characteristics of Vancomycin Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus at Hershey Medical Center
Antimicrob. Agents Chemother. 2008 52: 4510-4513. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Clinical Therapeutics:

George O. Adjei, Kim Kristensen, Bamenla Q. Goka, Lotte C. G. Hoegberg, Michael Alifrangis, Onike P. Rodrigues, and Jorgen A. L. Kurtzhals

Effect of Concomitant Artesunate Administration and Cytochrome P4502C8 Polymorphisms on the Pharmacokinetics of Amodiaquine in Ghanaian Children with Uncomplicated Malaria
Antimicrob. Agents Chemother. 2008 52: 4400-4406. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Ko-Chun Ko, Binghe Wang, Phang C. Tai, and Charles D. Derby

Identification of Potent Bactericidal Compounds Produced by Escapin, an L-Amino Acid Oxidase in the Ink of the Sea Hare Aplysia californica
Antimicrob. Agents Chemother. 2008 52: 4455-4462. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Hiromi Sato and Jimmy B. Feix

Lysine-Enriched Cecropin-Mellitin Antimicrobial Peptides with Enhanced Selectivity
Antimicrob. Agents Chemother. 2008 52: 4463-4465. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

Karin Streker, Tina Schäfer, Christoph Freiberg, Heike Brötz-Oesterhelt, Jörg Hacker, Harald Labischinski, and Knut Ohlsen

In Vitro and In Vivo Validation of ligA and tarI as Essential Targets in Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 4470-4474. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Béatrice Berçot, Laurent Poirel, and Patrice Nordmann

Plasmid-Mediated 16S rRNA Methylases among Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Isolates
Antimicrob. Agents Chemother. 2008 52: 4526-4527. [Full Text] [PDF] [Reprints and Permissions]  

V. Prakash, J. S. Lewis, II, and J. H. Jorgensen

Vancomycin MICs for Methicillin-Resistant Staphylococcus aureus Isolates Differ Based upon the Susceptibility Test Method Used
Antimicrob. Agents Chemother. 2008 52: 4528. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.